Home플랫폼과 전략논문 &학회발표
Phase 1 Trial Safety and Efficacy of Ragistomig, a Bispecific Antibody Targeting PD-L1 and 4-1BB in Advanced Solid Tumors
ABL503 (TJ-L14B), PD-L1×4-1BB bispecific antibody, reinvigorates exhausted tumor-infiltrating CD8+ T cells and synergizes with PD-1 blockade
The HER2/4-1BB bispecific antibody, YH32367 (ABL105) demonstrates optimal efficacy and safety for HER2-expressing tumors and exhibits synergistic efficacy when combined with anti-PD-1 antibody
ABL407, a LILRB4x4-1BB Bispecific Antibody with a Wild Type Fc, Exhibits Potent Antitumor Activity by Modulating Immune System in Multiple Ways Involving T cells, Myeloids, and Regulatory T cells
A Novel TIGIT and 4-1BB Bispecific Antibody, ABL112, Exhibits Potent in vitroand in vivo Antitumor Activity Through Dual Immune Modulation
PEGS Europe 2023 / ABL103, a novel B7-H4x4-1BB bispecific antibody, exerts potent antitumor activity and good safety profile via B7-H4-dependent 4-1BB activation with increased immune cell infiltration in tumor microenvironment
PEGS Europe 2023 / ROR1 targeted 4-1BB conditional bispecific antibody, ABL102, exhibits potent in vitro and in vivo antitumor activity and superior safety profile
CVB2023 / Grabody B, an IGF1 receptor based shuttle, mediates efficient delivery of biologics across the blood brain barrier
AACR2023 / ROR1 Targeted 4-1BB Stimulatory Bispecific Antibody, ABL102, Exhibits Potent in vitro and in vivo Antitumor Activity and Superior Safety Profile
AACR2023 / Preclinical study of a novel anti-CLEC12A antibody-drug conjugate with a glucuronideprotected pyrrolobenzodiazepine payload